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Antiseptics and mouthwashes: chlorhexidine

General and Dental Pharmacology · Dental (BDS)

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Why is chlorhexidine prescribed for short courses (1–2 weeks) rather than daily forever? Chlorhexidine's substantivity gives excellent plaque control, but prolonged use causes brown staining of teeth and tongue and alters taste. Teaching therefore positions it as a short-term adjunct — e.g., after periodontal procedures or when brushing is difficult — while daily lifelong plaque control stays mechanical (brush and floss).

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