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Immunology: complement, hypersensitivity, autoimmunity

Microbiology · MBBS

Animal cell explorer

Interactive 3D

Peek inside an animal cell — pick an organelle to highlight it and learn its job.

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Study notes

A peanut-eating child collapses — wheezing, hives, hypotension; adrenaline saves. Type I hypersensitivity (IgE-mediated): peanut crosslinks mast-cell IgE — histamine flood → vasodilation, bronchospasm, edema. IM adrenaline reverses all three (vasoconstrict, bronchodilate, reduce edema); antihistamines/steroids are adjuncts. EpiPen carriage + avoidance + action plan is the management. The immune system's overreaction is the disease — adrenaline is the reset button.

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