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Cutaneous manifestations of systemic disease

Dermatology, Venereology and Leprosy · MBBS

Study notes

Velvety dark neck — acanthosis nigricans; diabetes; check glucose. Cutaneous systemic: diabetes (acanthosis nigricans — insulin resistance; necrobiosis lipoidica — shins; infections), thyroid (pretibial myxedema — Graves; vitiligo — Hashimoto), liver (spider angioma, palmar erythema, jaundice), kidney (uremic frost, half-and-half nails), lupus (malar rash — photosensitive), paraneoplastic (acanthosis — gastric; Leser-Trelat — seborrheic keratoses — GI). The velvety neck is acanthosis — check sugar.

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