Compartmental models
General · Mathematics
Study notes
Q: Drug: gut → blood → eliminated. Write compartmental equations. Gut G: dG/dt = -k_a G (absorption). Blood B: dB/dt = k_a G-k_e B (in minus out). Mass balance: what leaves one enters next! k_a: absorption rate, k_e: elimination. Solve: G = G₀e^(-k_a t), B rises then falls! (Compartments: tracking flows!)