CNS drugs: sedatives, hypnotics, antiepileptics
Pharmacology · MBBS
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Study notes
A patient seizing for 10 minutes gets IV lorazepam, then fosphenytoin. This is status epilepticus protocol — benzodiazepine first (lorazepam/diazepam stops the seizure by boosting GABA inhibition), then a longer-acting agent (fosphenytoin, valproate, or levetiracetam) prevents recurrence. Beyond 30 minutes, neurons die — status is a race: benzo at 5 minutes, second drug at 20, anesthesia beyond. Every minute seizing kills brain — the protocol is timed like resuscitation.
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