General pharmacology: pharmacodynamics — receptors, dose-response, drug interactions
Pharmacology · MBBS
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Study notes
Two blood pressure drugs together drop pressure more than either alone. This is synergism — an ACE inhibitor (blocks angiotensin) plus a diuretic (reduces volume) attack hypertension by two mechanisms, each boosting the other. Contrast antagonism: naloxone (opioid antagonist) reverses morphine overdose — blocking the same receptor. Prescribers combine for synergy (TB's four drugs, heart failure cocktails) and avoid antagonistic pairs — interaction is pharmacodynamics in practice.
Related topics
- General pharmacology: pharmacokinetics — absorption, distribution, metabolism, excretion
- General pharmacology: adverse drug reactions, pharmacovigilance
- Autonomic drugs: cholinergic agonists and antagonists
- Autonomic drugs: adrenergic agonists and antagonists
- Cardiovascular drugs: antihypertensives, antianginal drugs
- Cardiovascular drugs: heart failure drugs, antiarrhythmics, lipid-lowering drugs